Liberal transfusion af røde donorblodceller kan øge mortaliteten

Hans Christian Pommergaard*, Astrid Nørgaard, Jakob Burcharth, Trine Stissing, Jacob Rosenberg

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstract

    In addition to the known adverse effects of red blood cell transfusion, evidence suggests that transfusion with allogeneic red blood cells in itself may increase mortality, risk of infection and even cancer recurrence rates. Among possible mechanisms to explain this effect are transfusion-related immune modulation and storage lesions. However, anaemia may also increase mortality and the risk of anaemia should be balanced against the risks of transfusion. Further properly designed and powered studies are needed to clarify the beneficial and harmful effects of red blood cell transfusion in well-defined patient categories.

    Bidragets oversatte titelLiberal red blood cell transfusion may increase mortality
    OriginalsprogDansk
    Sider (fra-til)630-633
    Antal sider4
    TidsskriftUgeskrift for laeger
    Udgave nummer7
    StatusUdgivet - 1 jan. 2014

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