Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment

Hanne Dorthe Emborg; T. G. Krause; L. Nielsen; M. K. Thomsen; C. B. Christiansen; M. N. Skov; X. C. Nielsen; L. S. Weinreich; T. K. Fischer; J. Rønn; R. Trebbien

doi:10.2807/1560-7917.ES.2016.21.14.30189

Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment

Hanne Dorthe Emborg^*, T. G. Krause, L. Nielsen, M. K. Thomsen, C. B. Christiansen, M. N. Skov, X. C. Nielsen, L. S. Weinreich, T. K. Fischer, J. Rønn, R. Trebbien

^*Corresponding author af dette arbejde

Klinisk Mikrobiologisk Afdeling

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstract

In Denmark, both influenza A(H1N1)pdm09 and influenza B co-circulated in the 2015/16 season. We estimated the vaccine effectiveness (VE) of the trivalent influenza vaccine in patients 65 years and older using the test-negative case–control design. The adjusted VE against influenza A(H1N1)pdm09 was 35.0% (95% confidence interval (CI): 11.1–52.4) and against influenza B 4.1% (95% CI: −22.0 to 24.7). The majority of influenza A(H1N1)pdm09 circulating in 2015/16 belonged to the new genetic subgroup subclade 6B.1.

Originalsprog	Engelsk
Tidsskrift	Eurosurveillance
Vol/bind	21
Udgave nummer	14
DOI	https://doi.org/10.2807/1560-7917.ES.2016.21.14.30189
Status	Udgivet - 7 apr. 2016

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Emborg, H. D., Krause, T. G., Nielsen, L., Thomsen, M. K., Christiansen, C. B., Skov, M. N., Nielsen, X. C., Weinreich, L. S., Fischer, T. K., Rønn, J., & Trebbien, R. (2016). Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment. Eurosurveillance, 21(14). https://doi.org/10.2807/1560-7917.ES.2016.21.14.30189

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title = "Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment",

abstract = "In Denmark, both influenza A(H1N1)pdm09 and influenza B co-circulated in the 2015/16 season. We estimated the vaccine effectiveness (VE) of the trivalent influenza vaccine in patients 65 years and older using the test-negative case–control design. The adjusted VE against influenza A(H1N1)pdm09 was 35.0% (95% confidence interval (CI): 11.1–52.4) and against influenza B 4.1% (95% CI: −22.0 to 24.7). The majority of influenza A(H1N1)pdm09 circulating in 2015/16 belonged to the new genetic subgroup subclade 6B.1.",

author = "Emborg, {Hanne Dorthe} and Krause, {T. G.} and L. Nielsen and Thomsen, {M. K.} and Christiansen, {C. B.} and Skov, {M. N.} and Nielsen, {X. C.} and Weinreich, {L. S.} and Fischer, {T. K.} and J. R{\o}nn and R. Trebbien",

year = "2016",

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language = "English",

volume = "21",

journal = "Eurosurveillance",

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Emborg, HD, Krause, TG, Nielsen, L, Thomsen, MK, Christiansen, CB, Skov, MN, Nielsen, XC, Weinreich, LS, Fischer, TK, Rønn, J & Trebbien, R 2016, 'Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment', Eurosurveillance, bind 21, nr. 14. https://doi.org/10.2807/1560-7917.ES.2016.21.14.30189

TY - JOUR

T1 - Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment

AU - Emborg, Hanne Dorthe

AU - Krause, T. G.

AU - Nielsen, L.

AU - Thomsen, M. K.

AU - Christiansen, C. B.

AU - Skov, M. N.

AU - Nielsen, X. C.

AU - Weinreich, L. S.

AU - Fischer, T. K.

AU - Rønn, J.

AU - Trebbien, R.

PY - 2016/4/7

Y1 - 2016/4/7

N2 - In Denmark, both influenza A(H1N1)pdm09 and influenza B co-circulated in the 2015/16 season. We estimated the vaccine effectiveness (VE) of the trivalent influenza vaccine in patients 65 years and older using the test-negative case–control design. The adjusted VE against influenza A(H1N1)pdm09 was 35.0% (95% confidence interval (CI): 11.1–52.4) and against influenza B 4.1% (95% CI: −22.0 to 24.7). The majority of influenza A(H1N1)pdm09 circulating in 2015/16 belonged to the new genetic subgroup subclade 6B.1.

AB - In Denmark, both influenza A(H1N1)pdm09 and influenza B co-circulated in the 2015/16 season. We estimated the vaccine effectiveness (VE) of the trivalent influenza vaccine in patients 65 years and older using the test-negative case–control design. The adjusted VE against influenza A(H1N1)pdm09 was 35.0% (95% confidence interval (CI): 11.1–52.4) and against influenza B 4.1% (95% CI: −22.0 to 24.7). The majority of influenza A(H1N1)pdm09 circulating in 2015/16 belonged to the new genetic subgroup subclade 6B.1.

UR - http://www.scopus.com/inward/record.url?scp=84963612106&partnerID=8YFLogxK

U2 - 10.2807/1560-7917.ES.2016.21.14.30189

DO - 10.2807/1560-7917.ES.2016.21.14.30189

M3 - Article

C2 - 27101732

AN - SCOPUS:84963612106

SN - 1025-496X

VL - 21

JO - Eurosurveillance

JF - Eurosurveillance

IS - 14

ER -

Influenza vaccine effectiveness in adults 65 years and older, Denmark, 2015/16 – A rapid epidemiological and virological assessment

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