Increased myelosuppression during cytostatic treatment and pleural effusion in patients with small cell lung cancer

Jørn Herrtedt, Paul Clementsen, Ole Paaske Hansen

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    30 patients with small cell lung cancer (SCLC) and malignant pleural effusion were compared with 30 matched patients with SCLC but without pleural effusion. In the 30 with pleural effusion, white blood cell and platelet counts fell significantly after initial chemotherapy, necessitating dose reduction. Of the patients with pleural effusion, 16 developed severe (WHO grade IV) leukopenia, 7 had severe thrombocytopenia, and 2 patients died of infection. Accordingly, exhaustive aspiration of radiologically verified pleural effusion before starting chemotherapy in patients with SCLC is recommended.

    OriginalsprogEngelsk
    Sider (fra-til)1070-1073
    Antal sider4
    TidsskriftEuropean Journal of Cancer
    Vol/bind28
    Udgave nummer6-7
    DOI
    StatusUdgivet - maj 1992

    Fingeraftryk Udforsk hvilke forskningsemner 'Increased myelosuppression during cytostatic treatment and pleural effusion in patients with small cell lung cancer' indeholder.

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