TY - JOUR
T1 - Incidence of pelvic organ prolapse repair subsequent to hysterectomy
T2 - a comparison between radical hysterectomy and total abdominal hysterectomy
AU - Lykke, Rune
AU - Blaakær, Jan
AU - Ottesen, Bent
AU - Gimbel, Helga
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Introduction and hypothesis: The aim of this study was to compare the incidence of subsequent pelvic organ prolapse (POP) repair in women following radical hysterectomy versus total abdominal hysterectomy. Methods: From the Danish National Patient Registry, we collected data on all radical hysterectomies, all total abdominal hysterectomies, and all POP operations performed in Denmark from 1 January 1977 to 31 December 2009. We excluded patients with prior POP repair, POP diagnosis, or concomitant POP repair at hysterectomy. We analyzed the incidence of POP surgery using Kaplan–Meier curves and hazard ratio (HR). Results: In all, 5279 women underwent radical hysterectomy, and 63 of these underwent subsequent POP surgery. In the same period, 149,920 women underwent total abdominal hysterectomy, and 6107 of these had POP surgery subsequent to the hysterectomy. The cumulative incidence of POP surgery was significantly lower for radical hysterectomy than for abdominal hysterectomy—3.4 % and 9.5 %, respectively, at the end of the study period, yielding a crude HR of 0.36 and an adjusted HR of 0.40 in favor of the radical hysterectomy. The distribution of POP operations in the defined compartments was the same for the two types of hysterectomy. Conclusions: This study found a significantly lower incidence of subsequent POP operations among women who undergo radical hysterectomy than total abdominal hysterectomy.
AB - Introduction and hypothesis: The aim of this study was to compare the incidence of subsequent pelvic organ prolapse (POP) repair in women following radical hysterectomy versus total abdominal hysterectomy. Methods: From the Danish National Patient Registry, we collected data on all radical hysterectomies, all total abdominal hysterectomies, and all POP operations performed in Denmark from 1 January 1977 to 31 December 2009. We excluded patients with prior POP repair, POP diagnosis, or concomitant POP repair at hysterectomy. We analyzed the incidence of POP surgery using Kaplan–Meier curves and hazard ratio (HR). Results: In all, 5279 women underwent radical hysterectomy, and 63 of these underwent subsequent POP surgery. In the same period, 149,920 women underwent total abdominal hysterectomy, and 6107 of these had POP surgery subsequent to the hysterectomy. The cumulative incidence of POP surgery was significantly lower for radical hysterectomy than for abdominal hysterectomy—3.4 % and 9.5 %, respectively, at the end of the study period, yielding a crude HR of 0.36 and an adjusted HR of 0.40 in favor of the radical hysterectomy. The distribution of POP operations in the defined compartments was the same for the two types of hysterectomy. Conclusions: This study found a significantly lower incidence of subsequent POP operations among women who undergo radical hysterectomy than total abdominal hysterectomy.
KW - Hysterectomy
KW - Pelvic organ prolapse
KW - Radical hysterectomy
KW - Urogynecology
UR - http://www.scopus.com/inward/record.url?scp=84991584921&partnerID=8YFLogxK
U2 - 10.1007/s00192-016-3173-7
DO - 10.1007/s00192-016-3173-7
M3 - Article
C2 - 27752747
AN - SCOPUS:84991584921
SN - 0937-3462
VL - 28
SP - 745
EP - 749
JO - International Urogynecology Journal
JF - International Urogynecology Journal
IS - 5
ER -