Implementation of treatment recommendations for chronic hepatitis B in patients attending specialized hospital care in Denmark - a region wide study

Signe Bollerup, Sofie Hallager, Ole Baek, Henrik Krarup, Lone Galmstrup Madsen, Peter Thielsen, Ulla Balslev, Helene Mens, Toke Barfod, Mette Rye Clausen, Lise Hobolth, Jan Gerstoft, Nina Weis

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstract

Objective: To evaluate implementation of national guideline recommendations on treatment initiation for chronic hepatitis B (CHB) in Denmark.Methods: Using DANHEP, a nationwide cohort of chronic hepatitis B and C patients attending specialized hospital care in Denmark, we performed a descriptive cohort study from January 2002 through December 2017. We identified patients with CHB in 3 of 5 Danish regions, with at least two hospital/outpatient clinic visits during the study period.Results: We identified 990 CHB patients who remained untreated throughout the study period, and 265 who initiated treatment. At their last visit 952/990 (96%, 95% CI 95-97) untreated patients did not meet current national criteria for treatment initiation while 198/265 (75%, 95% CI 69-80) who initiated treatment met the national criteria. Overall, 198/236 (84%, 95% CI 79-88) who met national treatment criteria, initiated treatment.Conclusion: The majority of CHB patients received care in line with national guideline recommendations for treatment initiation. We found that only few patients eligible for treatment remained untreated. However, a fourth of patients who received treatment were not eligible according to national guidelines.

OriginalsprogEngelsk
Sider (fra-til)843-847
Antal sider5
TidsskriftScandinavian journal of gastroenterology
Vol/bind55
Udgave nummer7
DOI
StatusUdgivet - 2 jul. 2020

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