Immunterapiens rolle i behandlingen af kolorektalcancer

Adile Orhan; Sara Mørup; Laurids Østergaard Poulsen; Per Pfeiffer; Camilla Qvortrup; Ismail Gögenur

Immunterapiens rolle i behandlingen af kolorektalcancer

Adile Orhan, Sara Mørup, Laurids Østergaard Poulsen, Per Pfeiffer, Camilla Qvortrup, Ismail Gögenur

Publikation: Bidrag til tidsskrift › Review › Forskning › peer review

Abstract

In Denmark, around 4,500 people are diagnosed with colorectal cancer (CRC) annually. This review investigates that while the efficacy of immunotherapy in CRC is still being studied, immunotherapy is currently only indicated in the treatment of mismatch-repair deficient (dMMR) metastatic CRC, which accounts for 10-15% of patients. Recent studies indicate high rates of pathologic response in dMMR CRC treated with pre-operative immunotherapy while large-scale studies on novel immunotherapy combinations are ongoing.

Bidragets oversatte titel	The role of immunotherapy in the treatment of colorectal cancer
Originalsprog	Dansk
Artikelnummer	V06230371
Antal sider	8
Tidsskrift	Ugeskrift for laeger
Vol/bind	185
Udgave nummer	51
Status	Udgivet - 18 dec. 2023

Emneord

Humans
Immunotherapy
Colorectal Neoplasms/diagnosis
Colonic Neoplasms
Rectal Neoplasms

Adgang til dokumentet

https://ugeskriftet.dk/videnskab/immunterapiens-rolle-i-behandlingen-af-kolorektalcancer

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Immunterapiens rolle i behandlingen af kolorektalcancer
Orhan, A. (Fotograf), 17 maj 2024
Publikation: Bidrag der ikke har en tekstform › Digitale eller visuelle produkter › Formidling

Citationsformater

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title = "Immunterapiens rolle i behandlingen af kolorektalcancer",

abstract = "In Denmark, around 4,500 people are diagnosed with colorectal cancer (CRC) annually. This review investigates that while the efficacy of immunotherapy in CRC is still being studied, immunotherapy is currently only indicated in the treatment of mismatch-repair deficient (dMMR) metastatic CRC, which accounts for 10-15\% of patients. Recent studies indicate high rates of pathologic response in dMMR CRC treated with pre-operative immunotherapy while large-scale studies on novel immunotherapy combinations are ongoing.",

keywords = "Humans, Immunotherapy, Colorectal Neoplasms/diagnosis, Colonic Neoplasms, Rectal Neoplasms",

author = "Adile Orhan and Sara M{\o}rup and Poulsen, \{Laurids {\O}stergaard\} and Per Pfeiffer and Camilla Qvortrup and Ismail G{\"o}genur",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2023",

month = dec,

day = "18",

language = "Dansk",

volume = "185",

journal = "Ugeskrift for laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "51",

}

TY - JOUR

T1 - Immunterapiens rolle i behandlingen af kolorektalcancer

AU - Orhan, Adile

AU - Mørup, Sara

AU - Poulsen, Laurids Østergaard

AU - Pfeiffer, Per

AU - Qvortrup, Camilla

AU - Gögenur, Ismail

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2023/12/18

Y1 - 2023/12/18

N2 - In Denmark, around 4,500 people are diagnosed with colorectal cancer (CRC) annually. This review investigates that while the efficacy of immunotherapy in CRC is still being studied, immunotherapy is currently only indicated in the treatment of mismatch-repair deficient (dMMR) metastatic CRC, which accounts for 10-15% of patients. Recent studies indicate high rates of pathologic response in dMMR CRC treated with pre-operative immunotherapy while large-scale studies on novel immunotherapy combinations are ongoing.

AB - In Denmark, around 4,500 people are diagnosed with colorectal cancer (CRC) annually. This review investigates that while the efficacy of immunotherapy in CRC is still being studied, immunotherapy is currently only indicated in the treatment of mismatch-repair deficient (dMMR) metastatic CRC, which accounts for 10-15% of patients. Recent studies indicate high rates of pathologic response in dMMR CRC treated with pre-operative immunotherapy while large-scale studies on novel immunotherapy combinations are ongoing.

KW - Humans

KW - Immunotherapy

KW - Colorectal Neoplasms/diagnosis

KW - Colonic Neoplasms

KW - Rectal Neoplasms

M3 - Review

C2 - 38105736

SN - 0041-5782

VL - 185

JO - Ugeskrift for laeger

JF - Ugeskrift for laeger

IS - 51

M1 - V06230371

ER -

Immunterapiens rolle i behandlingen af kolorektalcancer

Abstract

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Publikation

Immunterapiens rolle i behandlingen af kolorektalcancer

Citationsformater