Hyperlipidaemi ved nefrotisk syndrom.

J. G. Heaf*

*Corresponding author af dette arbejde

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    Abstrakt

    Hyperlipidemia is common in patients with the nephrotic syndrome. The main cause is probably increased hepatic lipogenesis, a non-specific reaction to falling oncotic pressure secondary to hypoalbuminemia. Cardiovascular morbidity and mortality are increased in patients with the nephrotic syndrome, with the exception of patients with minimal change disease. It is not clear whether this is caused by the hypercholesterolemia or secondary to uremia or medical treatment. Experiments suggest that hypercholesterolemia may cause glomerulosclerosis, a common complication of the nephrotic syndrome. The hypercholesterolemia of the nephrotic syndrome can now be treated effectively with HMG coenzyme A reductase inhibitors.

    Bidragets oversatte titelHyperlipidemia in nephrotic syndrome
    OriginalsprogDansk
    Sider (fra-til)2414-2416
    Antal sider3
    TidsskriftUgeskrift for laeger
    Vol/bind153
    Udgave nummer35
    StatusUdgivet - 26 aug. 1991

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