High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation: A Prespecified Analysis of the DANFLU-2 Trial

Caroline Espersen; Niklas Dyrby Johansen; Daniel Modin; Matthew M Loiacono; Rebecca C Harris; Marine Dufournet; Carsten Schade Larsen; Lykke Larsen; Lothar Wiese; Michael Dalager-Pedersen; Brian L Claggett; Katja Vu Bartholdy; Katrine Feldballe Bernholm; Julie Inge-Marie Helene Borchsenius; Filip Søskov Davidovski; Lise Witten Davodian; Maria Dons; Lisa Steen Duus; Frederik Holme Fussing; Anne Marie Reimer Jensen; Nino Emanuel Landler; Adam Cadovius Femerling Langhoff; Mats Christian Højbjerg Lassen; Anne Bjerg Nielsen; Camilla Ikast Ottosen; Morten Sengeløv; Kristoffer Grundtvig Skaarup; Scott D Solomon; Martin J Landray; Gunnar H Gislason; Lars Køber; Pradeesh Sivapalan; Cyril Jean-Marie Martel; Jens Ulrik Stæhr Jensen; Tor Biering-Sørensen

doi:10.1016/j.jacc.2025.09.1578

High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation: A Prespecified Analysis of the DANFLU-2 Trial

Caroline Espersen
, Niklas Dyrby Johansen
, Daniel Modin
, Matthew M Loiacono
, Rebecca C Harris
, Marine Dufournet
, Carsten Schade Larsen
, Lykke Larsen
, Lothar Wiese
, Michael Dalager-Pedersen
, Brian L Claggett
, Katja Vu Bartholdy
, Katrine Feldballe Bernholm
, Julie Inge-Marie Helene Borchsenius
, Filip Søskov Davidovski
, Lise Witten Davodian
, Maria Dons
, Lisa Steen Duus
, Frederik Holme Fussing
, Anne Marie Reimer Jensen

Nino Emanuel Landler, Adam Cadovius Femerling Langhoff, Mats Christian Højbjerg Lassen, Anne Bjerg Nielsen, Camilla Ikast Ottosen, Morten Sengeløv, Kristoffer Grundtvig Skaarup, Scott D Solomon, Martin J Landray, Gunnar H Gislason, Lars Køber, Pradeesh Sivapalan, Cyril Jean-Marie Martel, Jens Ulrik Stæhr Jensen, Tor Biering-Sørensen

Medicinsk Afdeling Roskilde

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Originalsprog	Engelsk
Sider (fra-til)	2651-2655
Antal sider	5
Tidsskrift	Journal of the American College of Cardiology
Vol/bind	86
Udgave nummer	25
Tidlig onlinedato	12 nov. 2025
DOI	https://doi.org/10.1016/j.jacc.2025.09.1578
Status	Udgivet - 23 dec. 2025

Adgang til dokumentet

10.1016/j.jacc.2025.09.1578Licens: CC BY-NC-ND

Citationsformater

Espersen, C., Johansen, N. D., Modin, D., Loiacono, M. M., Harris, R. C., Dufournet, M., Larsen, C. S., Larsen, L., Wiese, L., Dalager-Pedersen, M., Claggett, B. L., Bartholdy, K. V., Bernholm, K. F., Borchsenius, J. I.-M. H., Davidovski, F. S., Davodian, L. W., Dons, M., Duus, L. S., Fussing, F. H., ... Biering-Sørensen, T. (2025). High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation: A Prespecified Analysis of the DANFLU-2 Trial. Journal of the American College of Cardiology, 86(25), 2651-2655. https://doi.org/10.1016/j.jacc.2025.09.1578

@article{62ecb230e2ab47559390a5cb7e957831,

title = "High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation: A Prespecified Analysis of the DANFLU-2 Trial",

keywords = "Atrial fibrillation, High-dose, Hospitalizations, Influenza, Pragmatic, Randomized controlled trial, Registry, Vaccination",

author = "Caroline Espersen and Johansen, \{Niklas Dyrby\} and Daniel Modin and Loiacono, \{Matthew M\} and Harris, \{Rebecca C\} and Marine Dufournet and Larsen, \{Carsten Schade\} and Lykke Larsen and Lothar Wiese and Michael Dalager-Pedersen and Claggett, \{Brian L\} and Bartholdy, \{Katja Vu\} and Bernholm, \{Katrine Feldballe\} and Borchsenius, \{Julie Inge-Marie Helene\} and Davidovski, \{Filip S{\o}skov\} and Davodian, \{Lise Witten\} and Maria Dons and Duus, \{Lisa Steen\} and Fussing, \{Frederik Holme\} and \{Reimer Jensen\}, \{Anne Marie\} and Landler, \{Nino Emanuel\} and \{Femerling Langhoff\}, \{Adam Cadovius\} and Lassen, \{Mats Christian H{\o}jbjerg\} and Nielsen, \{Anne Bjerg\} and Ottosen, \{Camilla Ikast\} and Morten Sengel{\o}v and Skaarup, \{Kristoffer Grundtvig\} and Solomon, \{Scott D\} and Landray, \{Martin J\} and Gislason, \{Gunnar H\} and Lars K{\o}ber and Pradeesh Sivapalan and Martel, \{Cyril Jean-Marie\} and Jensen, \{Jens Ulrik St{\ae}hr\} and Tor Biering-S{\o}rensen",

year = "2025",

month = dec,

day = "23",

doi = "10.1016/j.jacc.2025.09.1578",

language = "English",

volume = "86",

pages = "2651--2655",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier",

number = "25",

}

Espersen, C, Johansen, ND, Modin, D, Loiacono, MM, Harris, RC, Dufournet, M, Larsen, CS, Larsen, L, Wiese, L, Dalager-Pedersen, M, Claggett, BL, Bartholdy, KV, Bernholm, KF, Borchsenius, JI-MH, Davidovski, FS, Davodian, LW, Dons, M, Duus, LS, Fussing, FH, Reimer Jensen, AM, Landler, NE, Femerling Langhoff, AC, Lassen, MCH, Nielsen, AB, Ottosen, CI, Sengeløv, M, Skaarup, KG, Solomon, SD, Landray, MJ, Gislason, GH, Køber, L, Sivapalan, P, Martel, CJ-M, Jensen, JUS & Biering-Sørensen, T 2025, 'High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation: A Prespecified Analysis of the DANFLU-2 Trial', Journal of the American College of Cardiology, bind 86, nr. 25, s. 2651-2655. https://doi.org/10.1016/j.jacc.2025.09.1578

TY - JOUR

T1 - High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Atrial Fibrillation

T2 - A Prespecified Analysis of the DANFLU-2 Trial

AU - Espersen, Caroline

AU - Johansen, Niklas Dyrby

AU - Modin, Daniel

AU - Loiacono, Matthew M

AU - Harris, Rebecca C

AU - Dufournet, Marine

AU - Larsen, Carsten Schade

AU - Larsen, Lykke

AU - Wiese, Lothar

AU - Dalager-Pedersen, Michael

AU - Claggett, Brian L

AU - Bartholdy, Katja Vu

AU - Bernholm, Katrine Feldballe

AU - Borchsenius, Julie Inge-Marie Helene

AU - Davidovski, Filip Søskov

AU - Davodian, Lise Witten

AU - Dons, Maria

AU - Duus, Lisa Steen

AU - Fussing, Frederik Holme

AU - Reimer Jensen, Anne Marie

AU - Landler, Nino Emanuel

AU - Femerling Langhoff, Adam Cadovius

AU - Lassen, Mats Christian Højbjerg

AU - Nielsen, Anne Bjerg

AU - Ottosen, Camilla Ikast

AU - Sengeløv, Morten

AU - Skaarup, Kristoffer Grundtvig

AU - Solomon, Scott D

AU - Landray, Martin J

AU - Gislason, Gunnar H

AU - Køber, Lars

AU - Sivapalan, Pradeesh

AU - Martel, Cyril Jean-Marie

AU - Jensen, Jens Ulrik Stæhr

AU - Biering-Sørensen, Tor

PY - 2025/12/23

Y1 - 2025/12/23

KW - Atrial fibrillation

KW - High-dose

KW - Hospitalizations

KW - Influenza

KW - Pragmatic

KW - Randomized controlled trial

KW - Registry

KW - Vaccination

U2 - 10.1016/j.jacc.2025.09.1578

DO - 10.1016/j.jacc.2025.09.1578

M3 - Article

C2 - 41295941

SN - 0735-1097

VL - 86

SP - 2651

EP - 2655

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 25

ER -