TY - JOUR
T1 - Hidradenitis Suppurativa Prevalence in Indonesia
T2 - A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire
AU - Dewi, Shinta Trilaksmi
AU - Suryawati, Nyoman
AU - Indrastuti, Niken
AU - Bouazzi, Dorra
AU - Medianfar, Cecilia E
AU - Christensen, Robin
AU - Jemec, Gregor B E
AU - Chandran, Nisha S
AU - Pangastuti, Miranti
AU - Adji, Aryani
AU - Akhyar, Gardenia
AU - Nopriyati, Nopriyati
AU - Hazlianda, Cut Putri
AU - Febriana, Sri Awalia
N1 - © 2025 The Author(s). Published by S. Karger AG, Basel.
PY - 2025
Y1 - 2025
N2 - UNLABELLED: Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.RESULTS: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).CONCLUSION: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases. .
AB - UNLABELLED: Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.METHODS: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.RESULTS: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).CONCLUSION: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases. .
KW - Hidradenitis suppurativa
KW - Indonesia
KW - Multicenter
KW - Prevalence
KW - Questionnaire
KW - Cross-Sectional Studies
KW - Humans
KW - Middle Aged
KW - Hidradenitis Suppurativa/epidemiology
KW - Indonesia/epidemiology
KW - Male
KW - Young Adult
KW - Female
KW - Adult
KW - Surveys and Questionnaires
KW - Mass Screening/methods
U2 - 10.1159/000539705
DO - 10.1159/000539705
M3 - Article
C2 - 40623394
SN - 1018-8665
VL - 241
SP - 57
EP - 62
JO - Dermatology
JF - Dermatology
IS - Suppl. 1
ER -