Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - A prospective cohort study

Katrine K. Hedengran, Dick Nelson, Malene R. Andersen, Steen Stender, Pal B. Szecsi

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    Abstrakt

    Objective: To investigate hepcidin during pregnancy, delivery and postpartum in women with sufficient iron supplementation.Methods: Hepcidin was measured using LC-MS spectroscopy in 37 women during pregnancy, delivery and postpartum period in this longitudinal study.Results: Hepcidin was low during pregnancy and increased at delivery and postpartum. No correlations with inflammatory markers or iron metabolism were observed during pregnancy; at delivery a correlation with inflammatory markers was observed.Conclusion: During pregnancy, in women with sufficient iron supplementation, hepcidin is low and does not reflect iron status. During delivery and the postpartum period, hepcidin functions as a marker of inflammation.

    OriginalsprogEngelsk
    Sider (fra-til)1506-1508
    Antal sider3
    TidsskriftJournal of Maternal-Fetal and Neonatal Medicine
    Vol/bind29
    Udgave nummer9
    DOI
    StatusUdgivet - 2 maj 2016

    Fingeraftryk Udforsk hvilke forskningsemner 'Hepcidin levels are low during pregnancy and increase around delivery in women without iron deficiency - A prospective cohort study' indeholder.

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