Hairy‐cell leukaemia simulating connective tissue disease

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    A patient is reported, in whom clinical and biochemical evidence of connective tissue disease preceded the diagnosis of hairy‐cell leukaemia by at least 2 years. The pathogenetic mechanism(s) responsible for the coexistence of hairy‐cell leukaemia with vasculitis and rheumatic disease is discussed. It is proposed that the 2 diseases may share a common predisposing factor, or that the hairy cells may elicit disturbances in immune homeostasis, implying a dysfunction of T suppressor cells. Hairy‐cell leukaemia should be considered in the differential diagnosis in cases of unexplained febrile illness associated with pancytopenia and signs of connective tissue disease.

    Sider (fra-til)457-460
    Antal sider4
    TidsskriftScandinavian Journal of Haematology
    Udgave nummer5
    StatusUdgivet - maj 1984

    Fingeraftryk Udforsk hvilke forskningsemner 'Hairy‐cell leukaemia simulating connective tissue disease' indeholder.