Graft patency after off-pump versus on-pump coronary artery surgery in high-risk patients

Christian H. Møller, Mario J. Perko, Jens T. Lund, Lars W. Andersen, Henning Kelbæk, Jan K. Madsen, Christian Gluud, Daniel A. Steinbrchel

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    Objective. To compare angiographic graft patency in high-risk patients randomly allocated to off-pump vs. on-pump coronary artery bypass grafting (CABG). Design. From a randomised, single-centre clinical trial including patients undergoing isolated first-time coronary bypass surgery a subgroup of patients were scheduled to 1-year coronary angiographic follow-up. Patients had 3-vessel disease and a EuroSCORE ≥5. We evaluated graft patency using a patency index (percentage of patent grafts out of the total number of grafts in each patient). Results. One-year angiography was performed in 34 patients undergoing off-pump surgery and 35 patients undergoing on-pump surgery. The mean number of distal anastomoses was 3.38±0.65 in the off-pump group versus 3.46±0.61 in the on-pump group (NS). The number of patients without graft failure was 22 in the off-pump group and 24 in the on-pump group (NS). The overall patency index was 85% in the off-pump group versus 87% in the on-pump group with a mean difference of 2.1%, 95% confidence interval 12.9 to 8.7 (NS). Conclusions. In patients with 3-vessel disease and a high-risk profile we found no statistically significant difference in graft patency between off-pump and on-pump CABG at 1-year coronary angiographic follow-up.

    Sider (fra-til)161-167
    Antal sider7
    TidsskriftScandinavian Cardiovascular Journal
    Udgave nummer3
    StatusUdgivet - 3 jun. 2010


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