Gene delivery by electroporation

Julie Gehl*

*Corresponding author af dette arbejde

    Publikation: Bidrag til bog/antologi/rapportKapitelForskningpeer review

    Abstrakt

    By applying brief electric pulses, it is possible to transfer molecules into cells and tissues. The use of electroporation for delivery of chemotherapy is now quite widely used and in further development. Electrochemotherapy is in routine use for cutaneous tumors [1] in more than 100 cancer centers, and several thousand patients have been treated. Response rates are high and side effects limited [2-8]. An important perspective about the success of electrochemotherapy is that electroporation equipment approved for clinical use is now available in many hospitals, allowing its use for gene therapy.

    OriginalsprogEngelsk
    TitelDrug Delivery
    UndertitelAn Integrated Clinical and Engineering Approach
    ForlagCRC Press
    Sider341-348
    Antal sider8
    ISBN (Elektronisk)9781466565951
    ISBN (Trykt)9781466565944
    DOI
    StatusUdgivet - 1 jan. 2017

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