Further studies on Hb canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

Ulf Froelund; Erik Sandbakken; Pal Szecsi; Henrik Birgens

doi:10.3109/03630269.2010.511593

Further studies on Hb canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

Ulf Froelund, Erik Sandbakken, Pal Szecsi, Henrik Birgens^*

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstrakt

A case of Hb Canebire [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebire variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

Originalsprog	Engelsk
Sider (fra-til)	495-499
Antal sider	5
Tidsskrift	Hemoglobin
Vol/bind	34
Udgave nummer	5
DOI	https://doi.org/10.3109/03630269.2010.511593
Status	Udgivet - 1 okt. 2010

Adgang til dokumentet

10.3109/03630269.2010.511593

Andre filer og links

http://www.scopus.com/inward/record.url?scp=77956918993&partnerID=8YFLogxK

Citationsformater

@article{e50fbacc3a4f4eea8b15e20e271bfa07,

title = "Further studies on Hb canebi{\`e}re [β12(G4)Asn→His], a low affinity hemoglobin variant",

abstract = "A case of Hb Canebire [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebire variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.",

keywords = "Codon 102, Hb Canebire, Low-affinity hemoglobin (Hb) variant",

author = "Ulf Froelund and Erik Sandbakken and Pal Szecsi and Henrik Birgens",

year = "2010",

month = oct,

day = "1",

doi = "10.3109/03630269.2010.511593",

language = "English",

volume = "34",

pages = "495--499",

journal = "Hemoglobin",

issn = "0363-0269",

publisher = "Informa Healthcare",

number = "5",

}

TY - JOUR

T1 - Further studies on Hb canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

AU - Froelund, Ulf

AU - Sandbakken, Erik

AU - Szecsi, Pal

AU - Birgens, Henrik

PY - 2010/10/1

Y1 - 2010/10/1

N2 - A case of Hb Canebire [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebire variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

AB - A case of Hb Canebire [β102(G4)Asn→His] was diagnosed in an otherwise healthy 21-year-old Danish woman. The clinical consequences were minor, since her only symptom consisted of transient cyanosis in lips and fingers when exposed to cold environments. Whole blood p50 was 59.9 mmHg. The Hb Canebire variant could not be separated from Hb A by high performance liquid chromatography (HPLC) and isoelectric focusing (IEF), and it was thus missed by routine hemoglobin (Hb) fractionation techniques.

KW - Codon 102

KW - Hb Canebire

KW - Low-affinity hemoglobin (Hb) variant

UR - http://www.scopus.com/inward/record.url?scp=77956918993&partnerID=8YFLogxK

U2 - 10.3109/03630269.2010.511593

DO - 10.3109/03630269.2010.511593

M3 - Article

C2 - 20854124

AN - SCOPUS:77956918993

VL - 34

SP - 495

EP - 499

JO - Hemoglobin

JF - Hemoglobin

SN - 0363-0269

IS - 5

ER -

Further studies on Hb canebière [β12(G4)Asn→His], a low affinity hemoglobin variant

Abstrakt

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater