Fracture risk assessed by Fracture Risk Assessment Tool (FRAX) compared with fracture risk derived from population fracture rates

Katrine Hass Rubin, Bo Abrahamsen, Anne Pernille Hermann, Mickael Bech, Jeppe Gram, Kim Brixen

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    Purpose: To evaluate the performance of the Swedish version of Fracture Risk Assessment Tool (FRAX)) without bone mass density (BMD) in a Danish population to examine the possibility of applying this version to Danish women. Methods: From the Danish National Register of social security numbers, we randomly selected 5000 women living in the region of Southern Denmark aged 40—90 years to receive a mailed questionnaire concerning risk factors for osteoporosis based on FRAX. The predicted 10-year probability of hip fractures was calculated for each woman returning a complete questionnaire using the Swedish version of FRAX. The observed 10-year hip fracture risk was also calculated for each woman using age-specific hip fracture rates from the National Hospital Discharge Register and National survival tables. Results: A total of 4194 (84%) women responded to the questionnaire and 3636 (73%) gave complete information and were included in the analysis. Using FRAX, the predicted 10-year fracture risk was 7.6%, ranging from 0.3 to 25.0% at the age of 41—50 and 81—90, respectively, while the corresponding observed fracture risk was 7.6%, ranging from 0.4 to 24.0%, respectively and not significantly different from the predicted risk (p = 0.92). Conclusions: The Swedish version of FRAX without BMD is applicable to Danish women.

    OriginalsprogEngelsk
    Sider (fra-til)312-318
    Antal sider7
    TidsskriftScandinavian Journal of Public Health
    Vol/bind39
    Udgave nummer3
    DOI
    StatusUdgivet - maj 2011

    Fingeraftryk Udforsk hvilke forskningsemner 'Fracture risk assessed by Fracture Risk Assessment Tool (FRAX) compared with fracture risk derived from population fracture rates' indeholder.

    Citationsformater