Exposure to ultrafine particles and respiratory hospitalisations in five European cities

Evangelia Samoli*, Zorana Jovanovic Andersen, Klea Katsouyanni, Frauke Hennig, Thomas A.J. Kuhlbusch, Tom Bellander, Giorgio Cattani, Josef Cyrys, Francesco Forastiere, Bénédicte Jacquemin, Markku Kulmala, Timo Lanki, Steffen Loft, Andreas Massling, Aurelio Tobias, Massimo Stafoggia

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review


    Epidemiological evidence on the associations between exposure to ultrafine particles (UFP), with aerodynamic electrical mobility diameters <100 nm, and health is limited. We gathered data on UFP from five European cities within 2001-2011 to investigate associations between short-term changes in concentrations and respiratory hospitalisations. We applied city-specific Poisson regression models and combined city-specific estimates to obtain pooled estimates. We evaluated the sensitivity of our findings to co-pollutant adjustment and investigated effect modification patterns by period of the year, age at admission and specific diagnoses. Our results for the whole time period do not support an association between UFP and respiratory hospitalisations, although we found suggestive associations among those 0-14 years old. We nevertheless report consistent adverse effect estimates during the warm period of the year, statistically significant after lag 2 when an increase by 10000 particles per cm3 was associated with a 4.27% (95% CI 1.68-6.92%) increase in hospitalisations. These effect estimates were robust to particles' mass or gaseous pollutants adjustment. Considering that our findings during the warm period may reflect better exposure assessment and that the main source of non-soluble UFP in urban areas is traffic, our results call for improved regulation of traffic emissions.

    Sider (fra-til)674-682
    Antal sider9
    TidsskriftEuropean Respiratory Journal
    Udgave nummer3
    StatusUdgivet - 1 sep. 2016


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