TY - GEN
T1 - Evaluating enhancing the acute myocardial infarction criteria in the Glasgow electrocardiogram analysis program by including ST depression
AU - Clark, Elaine N.
AU - Sejersten, Maria
AU - Clemmensen, Peter
AU - MacFarlane, Peter W.
PY - 2010/12/1
Y1 - 2010/12/1
N2 - The aims of this study were to investigate if the acute myocardial infarction (MI) criteria in the University of Glasgow ECG analysis program (Uni-G) could be enhanced by including new lead pairings and to explore alternative criteria based on STEMI equivalence. 912 12-lead ECGs were recorded in ambulances on patients with a suspected acute coronary syndrome. The ACC/ESC and the Uni-G criteria were modified to include pairings {III,-aVL}, {-III,aVL}, and {-V2,-V3}. Using the hospital discharge diagnosis as the gold standard, the modified criteria were evaluated. Significant changes in sensitivity (SE) and specificity (SP) were evident using the modified ACC/ESC criteria: SEfrom 72.1% to 75.4% (p=0.002); SP from 88.1% to 86.6% (p=0.004). The current Uni-G criteria gave betterresults than the modified ACC/ESC criteria (SE 77.6% and SP 93.9%.). All attempts at extending the Uni-G criteria resulted in a decrease in SP.
AB - The aims of this study were to investigate if the acute myocardial infarction (MI) criteria in the University of Glasgow ECG analysis program (Uni-G) could be enhanced by including new lead pairings and to explore alternative criteria based on STEMI equivalence. 912 12-lead ECGs were recorded in ambulances on patients with a suspected acute coronary syndrome. The ACC/ESC and the Uni-G criteria were modified to include pairings {III,-aVL}, {-III,aVL}, and {-V2,-V3}. Using the hospital discharge diagnosis as the gold standard, the modified criteria were evaluated. Significant changes in sensitivity (SE) and specificity (SP) were evident using the modified ACC/ESC criteria: SEfrom 72.1% to 75.4% (p=0.002); SP from 88.1% to 86.6% (p=0.004). The current Uni-G criteria gave betterresults than the modified ACC/ESC criteria (SE 77.6% and SP 93.9%.). All attempts at extending the Uni-G criteria resulted in a decrease in SP.
UR - http://www.scopus.com/inward/record.url?scp=79953832516&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:79953832516
SN - 9781424473182
T3 - Computing in Cardiology
SP - 29
EP - 32
BT - Computing in Cardiology 2010, CinC 2010
T2 - Computing in Cardiology 2010, CinC 2010
Y2 - 26 September 2010 through 29 September 2010
ER -