Evaluating Danish Breast Cancer Group locoregional radiotherapy guideline adherence in clinical treatment data 2008-2016: The DBCG RT Nation study

Lasse Refsgaard*, Emma Skarsø Buhl, Esben Yates, Else Maae, Martin Berg, Sami Al-Rawi, Abhilasha Saini, Maja Vestmø Maraldo, Kristian Boye, Marie Louise Holm Milo, Ingelise Jensen, Louise Wichmann Matthiessen, Susanne Nørring Bekke, Mette Holck Nielsen, Ebbe Laugaard Lorenzen, Lise Bech Jellesmark Thorsen, Stine Sofia Korreman, Birgitte Vrou Offersen

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstract

BACKGROUND AND PURPOSE: Guideline adherence in radiotherapy is crucial for maintaining treatment quality and consistency, particularly in non-trial patient settings where most treatments occur. The study aimed to assess the impact of guideline changes on treatment planning practices and compare manual registry data accuracy with treatment planning data.

MATERIALS AND METHODS: This study utilised the DBCG RT Nation cohort, a collection of breast cancer radiotherapy data in Denmark, to evaluate adherence to guidelines from 2008 to 2016. The cohort included 7448 high-risk breast cancer patients. National guideline changes included, fractionation, introduction of respiratory gating, irradiation of the internal mammary lymph nodes, use of the simultaneous integrated boost technique and inclusion of the Left Anterior Descending coronary artery in delineation practice. Methods for structure name mapping, laterality detection, detection of temporal changes in population mean lung volume, and dose evaluation were presented and applied. Manually registered treatment characteristic data was obtained from the Danish Breast Cancer Database for comparison.

RESULTS: The study found immediate and consistent adherence to guideline changes across Danish radiotherapy centres. Treatment practices before guideline implementation were documented and showed a variation among centres. Discrepancies between manual registry data and actual treatment planning data were as high as 10% for some measures.

CONCLUSION: National guideline changes could be detected in the routine treatment data, with a high degree of compliance and short implementation time. Data extracted from treatment planning data files provides a more accurate and detailed characterisation of treatments and guideline adherence than medical register data.

OriginalsprogEngelsk
Artikelnummer110289
Antal sider6
TidsskriftRadiotherapy and Oncology
Vol/bind199
Tidlig onlinedato25 apr. 2024
DOI
StatusUdgivet - okt. 2024

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Copyright © 2024. Published by Elsevier B.V.

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