Enkeltcenteropgørelse af nyretransplanterede patienters nyrefunktion og immunsuppressive behandling

Anne Mette Frederiksen, Jesper Melchior Hansen, Bettina Ewers, Ane Gasbjerg, Peter Marckmann

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstrakt

    Introduction: The number of kidney-transplanted patients is growing. This report describes the age, sex distribution, kidney function, graft age, and immunosuppressive drugs of kidney-transplanted patients followed at the outpatient clinic of the nephrology department at Copenhagen University Hospital, Herlev, Denmark. Materials and methods: Cross-sectional study of all living kidney-transplanted patients with a functioning graft followed at Copenhagen University Hospital, Herlev (n=241). Data were extracted from patient records during November 2005 - March 2006. Results: The sex distribution (131 males, 110 females) was equal. The average patient age was 52 years (SD 12), the average glomerular filtration rate 43 ml/min/1.73m 2 (range 6-114 ml/min/1.73m 2 ), and the average graft age was 8.3 years (range 0-28 years). Hyperparathyroidism was highly prevalent (64%). The majority of patients (74%) were treated with triple-drug immunosuppression, in most cases (46%) with the combination prednisolone-ciclosporine-azathioprine. During recent years, azathioprine has been increasingly replaced by mycophenolate mofetil. Conclusions: The majority of kidney-transplanted patients with a functioning graft have sufficient kidney function to keep the patients free of uremic symptoms. Hyperparathyroidism is frequent. The immunosuppressive regimens used for kidney-transplanted patients are currently changing.

    Bidragets oversatte titelKidney function and immunosuppression of kidney-transplanted patients
    OriginalsprogDansk
    Sider (fra-til)1658-1662
    Antal sider5
    TidsskriftUgeskrift for laeger
    Vol/bind170
    Udgave nummer19
    StatusUdgivet - 5 maj 2008

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