Emerging antifungal treatment failure of dermatophytosis in Europe: take care or it may become endemic

Dml Saunte, M Pereiro-Ferreirós, C Rodríguez-Cerdeira, A Y Sergeev, M Arabatzis, A Prohić, B M Piraccini, P Lecerf, P Nenoff, L P Kotrekhova, P P Bosshard, V Padovese, J C Szepietowski, B Sigurgeirsson, R J Nowicki, P Schmid-Grendelmeier, R J Hay

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BACKGROUND: Dermatophytosis is a world-wide distributed common infection. Antifungal drug resistance in dermatophytosis used to be rare, but unfortunately the current Indian epidemic of atypical widespread recalcitrant and terbinafine-resistant dermatophytosis is spreading and has sporadically been reported in Europe.

OBJECTIVES: To explore the occurrence of clinical and mycological proven antifungal drug resistance in dermatophytes in Europe.

METHODS: A standardized questionnaire was distributed through the EADV Task Force of Mycology network to dermatologists in Europe.

RESULTS: Representatives from 20 countries completed the questionnaires of which 17 (85 %) had observed clinical and/or mycological confirmed antifungal resistance, two countries published cases of antifungal resistance and one country had no known cases.

CONCLUSIONS: This pilot study confirms that both clinical and mycological antifungal resistance exist in Europe.

Sider (fra-til)1582-1586
Antal sider5
TidsskriftJournal of the European Academy of Dermatology and Venereology : JEADV
Udgave nummer7
Tidlig onlinedato25 mar. 2021
StatusUdgivet - jul. 2021

Bibliografisk note

© 2021 European Academy of Dermatology and Venereology.


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