Delayed emesis: Moderately emetogenic chemotherapy

Fausto Roila; David Warr; Rebecca A. Clark-Snow; Maurizio Tonato; Richard J. Gralla; Lawrence H. Einhorn; Jorn Herrstedt

doi:10.1007/s00520-004-0700-8

Delayed emesis: Moderately emetogenic chemotherapy

Fausto Roila^*, David Warr, Rebecca A. Clark-Snow, Maurizio Tonato, Richard J. Gralla, Lawrence H. Einhorn, Jorn Herrstedt

^*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskrift › Review › Forskning › peer review

Abstract

Data on the incidence and efficacy of antiemetic prophylaxis against delayed emesis induced by moderately emetogenic chemotherapy are scanty. An overview of the literature has been done that showed the efficacy of dexamethasone in two of three randomized trials. Its optimal dose and duration of administration has not been defined. Only one of four randomized studies showed a statistically significant efficacy of 5-HT₃ antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists.

Originalsprog	Engelsk
Sider (fra-til)	104-108
Antal sider	5
Tidsskrift	Supportive Care in Cancer
Vol/bind	13
Udgave nummer	2
DOI	https://doi.org/10.1007/s00520-004-0700-8
Status	Udgivet - 1 feb. 2005

Adgang til dokumentet

10.1007/s00520-004-0700-8

Andre filer og links

http://www.scopus.com/inward/record.url?scp=17644396048&partnerID=8YFLogxK

Citationsformater

@article{51d124ac27dd4abda4151a728faa6f90,

title = "Delayed emesis: Moderately emetogenic chemotherapy",

abstract = "Data on the incidence and efficacy of antiemetic prophylaxis against delayed emesis induced by moderately emetogenic chemotherapy are scanty. An overview of the literature has been done that showed the efficacy of dexamethasone in two of three randomized trials. Its optimal dose and duration of administration has not been defined. Only one of four randomized studies showed a statistically significant efficacy of 5-HT3 antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists.",

keywords = "5-HT antagonist, Delayed emesis, Dexamethasone, Moderately emetogenic chemotherapy",

author = "Fausto Roila and David Warr and Clark-Snow, {Rebecca A.} and Maurizio Tonato and Gralla, {Richard J.} and Einhorn, {Lawrence H.} and Jorn Herrstedt",

year = "2005",

month = feb,

day = "1",

doi = "10.1007/s00520-004-0700-8",

language = "English",

volume = "13",

pages = "104--108",

journal = "Supportive Care in Cancer",

issn = "0941-4355",

publisher = "Springer Verlag",

number = "2",

}

TY - JOUR

T1 - Delayed emesis

T2 - Moderately emetogenic chemotherapy

AU - Roila, Fausto

AU - Warr, David

AU - Clark-Snow, Rebecca A.

AU - Tonato, Maurizio

AU - Gralla, Richard J.

AU - Einhorn, Lawrence H.

AU - Herrstedt, Jorn

PY - 2005/2/1

Y1 - 2005/2/1

N2 - Data on the incidence and efficacy of antiemetic prophylaxis against delayed emesis induced by moderately emetogenic chemotherapy are scanty. An overview of the literature has been done that showed the efficacy of dexamethasone in two of three randomized trials. Its optimal dose and duration of administration has not been defined. Only one of four randomized studies showed a statistically significant efficacy of 5-HT3 antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists.

AB - Data on the incidence and efficacy of antiemetic prophylaxis against delayed emesis induced by moderately emetogenic chemotherapy are scanty. An overview of the literature has been done that showed the efficacy of dexamethasone in two of three randomized trials. Its optimal dose and duration of administration has not been defined. Only one of four randomized studies showed a statistically significant efficacy of 5-HT3 antagonists. Finally, only weak evidence has been published on the efficacy of dopamine receptor antagonists.

KW - 5-HT antagonist

KW - Delayed emesis

KW - Dexamethasone

KW - Moderately emetogenic chemotherapy

UR - http://www.scopus.com/inward/record.url?scp=17644396048&partnerID=8YFLogxK

U2 - 10.1007/s00520-004-0700-8

DO - 10.1007/s00520-004-0700-8

M3 - Review

C2 - 15549426

AN - SCOPUS:17644396048

SN - 0941-4355

VL - 13

SP - 104

EP - 108

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

IS - 2

ER -

Delayed emesis: Moderately emetogenic chemotherapy

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater