TY - JOUR
T1 - Daytime and scheduled surgery for major dysvascular lower extremity amputation
AU - Ignatiussen, Martha Ella Thala Larsine Martine
AU - Pedersen, Poul
AU - Holm, Gitte
AU - Thomsen, Morten Grove
AU - Kristensen, Morten Tange
N1 - Articles published in the DMJ are “open access”. This means that the articles are distributed under the terms of the Creative Commons Attribution Non-commercial License, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
PY - 2023/2/17
Y1 - 2023/2/17
N2 - INTRODUCTION: Patients undergoing a major dysvascular lower extremity amputation (LEA) often have a poor outcome with a high risk of complications and mortality despite improvements in care and perioperative programmes. We evaluated whether scheduled surgery would reduce the failure rate in patients with a major LEA.METHODS: A total of 328 consecutive patients undergoing a major LEA from 2016 to 2019 were enrolled at a single centre. Early failure was defined as re-amputation or revision within 30 days of the index amputation. In 2018, a new regime comprising two scheduled surgery days was implemented. The risk of failure comparing the two cohorts (2016-2017, n = 165 versus 2018-2019, n = 163) was calculated for amputation on scheduled versus non-scheduled days and for other potentially influencing factors.RESULTS: The median (25-75% quartiles) age of all patients was 74 (66-83) years, 91% had an American Society of Anesthesiologists (ASA) grade ≥ 3 and 92% had atherosclerosis or diabetes mellitus. The index amputee levels were 36% below-knee, 60% transfemoral and 4% bilateral transfemoral. In the intervention cohort, 59% were amputated on the scheduled days versus 36% in the control group (p less-than 0.001). Correspondingly, more patients (72.4% versus 57.6%, p = 0.005) were amputated during daytime and the 30-day failure rate was reduced to 11.0% (n = 18) versus 16.4% (n = 27) (p = 0.2). Risk of failure on scheduled days in the intervention group was 8.3% versus 14.9% on any other day (p = 0.2). Correspondingly, daytime surgery reduced the risk of failure (6.8% versus 22.2%, p = 0.005).CONCLUSION: Daytime and scheduled surgery for major LEA may possibly reduce early risk of failure.FUNDING: none.TRIAL REGISTRATION: not relevant.
AB - INTRODUCTION: Patients undergoing a major dysvascular lower extremity amputation (LEA) often have a poor outcome with a high risk of complications and mortality despite improvements in care and perioperative programmes. We evaluated whether scheduled surgery would reduce the failure rate in patients with a major LEA.METHODS: A total of 328 consecutive patients undergoing a major LEA from 2016 to 2019 were enrolled at a single centre. Early failure was defined as re-amputation or revision within 30 days of the index amputation. In 2018, a new regime comprising two scheduled surgery days was implemented. The risk of failure comparing the two cohorts (2016-2017, n = 165 versus 2018-2019, n = 163) was calculated for amputation on scheduled versus non-scheduled days and for other potentially influencing factors.RESULTS: The median (25-75% quartiles) age of all patients was 74 (66-83) years, 91% had an American Society of Anesthesiologists (ASA) grade ≥ 3 and 92% had atherosclerosis or diabetes mellitus. The index amputee levels were 36% below-knee, 60% transfemoral and 4% bilateral transfemoral. In the intervention cohort, 59% were amputated on the scheduled days versus 36% in the control group (p less-than 0.001). Correspondingly, more patients (72.4% versus 57.6%, p = 0.005) were amputated during daytime and the 30-day failure rate was reduced to 11.0% (n = 18) versus 16.4% (n = 27) (p = 0.2). Risk of failure on scheduled days in the intervention group was 8.3% versus 14.9% on any other day (p = 0.2). Correspondingly, daytime surgery reduced the risk of failure (6.8% versus 22.2%, p = 0.005).CONCLUSION: Daytime and scheduled surgery for major LEA may possibly reduce early risk of failure.FUNDING: none.TRIAL REGISTRATION: not relevant.
KW - Aged
KW - Aged, 80 and over
KW - Amputation, Surgical
KW - Atherosclerosis
KW - Diabetes Mellitus
KW - Humans
KW - Knee Joint
KW - Lower Extremity/surgery
KW - Retrospective Studies
KW - Risk Factors
M3 - Article
C2 - 36896724
SN - 2245-1919
VL - 70
JO - Danish Medical Journal
JF - Danish Medical Journal
IS - 3
M1 - A07220435
ER -