Cohort profile: Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID:IBD) genetic cohort

  • Behrooz Darbani*
  • , Thorsten Brodersen
  • , Anette Liljensøe
  • , Signe Bek Sørensen
  • , Josephine Bjergbæk Olsson-Svendsen
  • , Alfonso Buil
  • , Ahmed Kamal
  • , Andrew J Schork
  • , Anja Poulsen
  • , Bertram Dalskov Kjerulff
  • , Bitten Aagaard
  • , Britta Ørnfelt Lund
  • , Charlotte Siggaard Rittig
  • , Christina Mikkelsen
  • , Daniel Millencourt Larsen
  • , David Westergaard
  • , Ditte Rudbeck-Resdal
  • , Dorte Helenius Mikkelsen
  • , Else Randers
  • , Frank Vinholt Schiødt
  • Hans Jürgen Hoffmann, Isabella Friis Jørgensen, Ivan Brandslund, Jacob Broder Brodersen, Jakob Hjorth von Stemann, Jakob Thaning Bay, Janna Nissen, Jeanette Sørensen, Jens Kjærgaard Boldsen, Joseph Dowsett, Josephine Gladov, Karina Banasik, Kathrine Agergård Kaspersen, Katrine Carlsen, Khoa Manh Dinh, Lauge Kellermann, Lea Arregui Nordahl Christoffersen, Liam James Elgaard Quinn, Lise Wegner Thørner, Lone Larsen, Luise Aamann, Malene Rohr Andersen, Maria Didriksen, Maria Joanna Alexandraki, Marianne Kragh Thomsen, Mette Julsgaard, Mette Nyegaard, Michael Schwinn, Mie Topholm-Bruun, Mikael Njai Leite, Morten Lee Halling, Natalia Pedersen, Ole K Bonderup, Palle Duun Rohde, Pernille Dige Ovesen, Ram Benny Dessau, Sanaz Saboori, Sofie Holm-Christensen, Steffen Bank, Susan Mikkelsen, Thomas Folkmann Hansen, Thomas Werge, Niels Qvist, Erik Sørensen, Johan Burisch, Merete Lund Hetland, Bente Glintborg, Christian Erikstrup, Søren Brunak, Henrik Ullum, Sisse Rye Ostrowski, Ole Birger Vesterager Pedersen, Vibeke Andersen
*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstract

The Copenhagen Hospital Biobank-chronic inflammatory disease-inflammatory bowel disease (CHB-CID: IBD) cohort contributes to genetic research in inflammatory bowel disease, including Crohn's disease and ulcerative colitis. Of the 327,084 enrolled and genotyped individuals in the cohort, 10,626 have been diagnosed with IBD as of May 2023. The CHB-CID: IBD cohort includes both patients without IBD and healthy blood donors as control groups. Clinical data is collected from Danish registries and patient records, including details on hospital contacts, co-morbidities, medication, surgical procedures, and laboratory investigations. The cohort features a wide age range (> 18 years), extensive population coverage representative of Danish adults, and validated IBD diagnoses. Finally, the cohort benefits from continuous recruitment and regular updates of clinical information. The aim is to enhance IBD management and ultimately improve patients' quality of life.

OriginalsprogEngelsk
Sider (fra-til)721-734
Antal sider14
TidsskriftEuropean Journal of Epidemiology
Vol/bind40
Udgave nummer6
Tidlig onlinedato9 jun. 2025
DOI
StatusUdgivet - jun. 2025

Finansiering

BevillingsgivereBevillingsgivernummer
Novo Nordisk FoundationNNF17OC0027594, NNF14CC0001

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