Abstract
Purpose: To study the acute impact of PTCA on LV-function and the effect of multiple balloon dilatations on global LVEF and ECG changes. Methods: LV-function was monitored in 40 patients using the Cardioscint system. Red blood cells were labeled with 800 Mbq Tc. Mean duration of balloon inflation: 113 ± 45 sec. Results: Pre-PTCA PTCA Post-PTCA LVEF: 63 ±.10 .51 ±.14* .65 ± .10* *P<0.05 LVEDC: 78 ± 19 79 ± 19 78 ± 19 LVESC: 29 ± 12 39 ± 16* 29 ± 12 LVEDC,LVESC: LV enddiastolic and endsystolic counts. 65%, 33% and 25% of the patients with LAD, CX and RCA disease, respectively had a decrease in LVEF > 10 EF units during PTCA. The decrease in LVEF and the return to post-PTCA levels occured within seconds after balloon inflation and deflation. 10 patients recived two consecutive and identical balloon dilatations: 1. PTCA 2.PTCA LVEF .41 ± .14 .44 ± .15* * P<0.05 STmax 294 ± 170 224 ± 150* STsum 102 ± 50 71 ± 46* STmax: The maximal ECG ST-segment deviation in a single lead. STsum: The mean of the ECG ST-segment deviations in 12 leads. Conclusion: There is a significant and abrupt decrease in LVEF during PTCA, explained by an increase in ESV with no change in EDV indicating a reduced contractility. The effect of dilatation on LVEF was more pronounced for LAD than CX and RCA. No patient showed any sign of post-PTCA stunning. In the 10 patients who recived two balloon dilatations the findings suggest that preconditioning can be induced in humans during PTCA.
Originalsprog | Engelsk |
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Antal sider | 1 |
Tidsskrift | Scandinavian Cardiovascular Journal, Supplement |
Vol/bind | 31 |
Udgave nummer | 45 |
Status | Udgivet - 1 dec. 1997 |