Cases of neuroleptic poisoning admitted to the Centre for Treatment of Poisoning in 1980

P. A.L. Bjaeldager, L. Breum, L. K. Munck

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    Out of 1,330 patients admitted to the Centre for the Treatment of Poisoning in 1980, 211 had taken neuroleptics. Thirty-three patients had pure neuroleptic poisoning while 178 had mixed poisoning. The patients within the various drug classes were subdivided into poisoning levels from 0 to 4. Where neuroleptica were concerned, this was undertaken on the basis of a retrospective assessment of the dosage ingested. In cases of mixed poisoning, neuroleptics were the most important drug, or as important as the other drug, or drugs, in 104 patients while neuroleptics were considered to be less important in 74 patients. These latter are not included in the results. The female/male ratio was 1.4 and 52% were in the age-group 20-39 years. Regular employment of neuroleptics was present in 60%. Poisoning levels 3 and 4 were found in 61% of the cases of pure neuroleptic poisoning as compared with 57% in the cases of mixed poisoning. 7/33 and 28/104 were soporose/comatose on admission. 10/33 and 53/104 had tachycardia while 2/33 and 9/104 had temperatures of under 35.5°C. Arterial hypotension occurred in 3/33 and 16/104 during hospitalization while disturbances of cardiac conduction or rhythm occurred in only 1/33 and 4/104. Unconsciousness for more than two hours occurred in 3/33 and 22/104 while 4/33 and 5/104 had convulsions. Mechanical ventilation for more than ten hours, possibly during relaxation and sedation, was included in the treatment in 1/33 and 8/104 while only 3/33 and 6/104 received blood or plasma. 3/104 were actively rewarmed while 1/33 and 3/104 were actively cooled. 27/33 and 78/104 were discharged within 24 hours while 1/33 and 6/104 were hospitalized for more than three days. None of the patients died. 45/133 were transferred for psychiatric treatment.

    Sider (fra-til)2972-2975
    Antal sider4
    TidsskriftUgeskrift for laeger
    Udgave nummer38
    StatusUdgivet - 1 jan. 1985


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