TY - JOUR
T1 - Association between widespread pain and psychosocial factors in people with knee osteoarthritis
T2 - a cross-sectional study of patients from primary care in Denmark
AU - Peral Pérez, Javier
AU - Mortensen, Sofie Rath
AU - Lluch Girbés, Enrique
AU - Grønne, Dorte T
AU - Thorlund, Jonas Bloch
AU - Roos, Ewa M
AU - Skou, Søren T
PY - 2025/4
Y1 - 2025/4
N2 - INTRODUCTION: The relationship between psychosocial factors and bodily pain in people with knee osteoarthritis (KOA) is unclear.PURPOSE: To examine whether widespread pain was associated with poorer self-efficacy, more anxiety, depression, and kinesiophobia in people with KOA.METHODS: This was a cross-sectional study based on data from Good Life with osteoArthritis in Denmark (GLA:D®). The association between widespread pain (multiple pain sites) and self-efficacy (Arthritis Self-Efficacy Scale), anxiety and depression (item from the EQ-5D-5 L), and kinesiophobia (yes/no) was examined using multiple linear tobit or logistic regression models.RESULTS: Among 19,323 participants, 10% had no widespread pain, 37% had 2 pain sites, 26% had 3-4 pain sites, and 27% had ≥5 pain sites. Widespread pain was associated with poorer self-efficacy (-0.9 to -8.3 points), and the association was stronger with increasing number of pain sites (p-value <.001). Significant increasing odds ratios (ORs) were observed for having anxiety or depression with 3-4 pain sites (OR 1.29, 95% CI 1.12; 1.49) and ≥5 pain sites (OR 1.80, 95% CI 1.56; 2.07). Having 2 and 3-4 pain sites were associated with lower odds of kinesiophobia compared to having no widespread pain.CONCLUSION: Widespread pain was associated with lower self-efficacy and more anxiety and depression but also lower kinesiophobia in people with KOA.
AB - INTRODUCTION: The relationship between psychosocial factors and bodily pain in people with knee osteoarthritis (KOA) is unclear.PURPOSE: To examine whether widespread pain was associated with poorer self-efficacy, more anxiety, depression, and kinesiophobia in people with KOA.METHODS: This was a cross-sectional study based on data from Good Life with osteoArthritis in Denmark (GLA:D®). The association between widespread pain (multiple pain sites) and self-efficacy (Arthritis Self-Efficacy Scale), anxiety and depression (item from the EQ-5D-5 L), and kinesiophobia (yes/no) was examined using multiple linear tobit or logistic regression models.RESULTS: Among 19,323 participants, 10% had no widespread pain, 37% had 2 pain sites, 26% had 3-4 pain sites, and 27% had ≥5 pain sites. Widespread pain was associated with poorer self-efficacy (-0.9 to -8.3 points), and the association was stronger with increasing number of pain sites (p-value <.001). Significant increasing odds ratios (ORs) were observed for having anxiety or depression with 3-4 pain sites (OR 1.29, 95% CI 1.12; 1.49) and ≥5 pain sites (OR 1.80, 95% CI 1.56; 2.07). Having 2 and 3-4 pain sites were associated with lower odds of kinesiophobia compared to having no widespread pain.CONCLUSION: Widespread pain was associated with lower self-efficacy and more anxiety and depression but also lower kinesiophobia in people with KOA.
KW - Aged
KW - Anxiety
KW - Arthralgia/psychology
KW - Cross-Sectional Studies
KW - Denmark
KW - Depression/psychology
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Osteoarthritis, Knee/psychology
KW - Pain Measurement
KW - Primary Health Care
KW - Self Efficacy
U2 - 10.1080/09593985.2024.2372381
DO - 10.1080/09593985.2024.2372381
M3 - Article
C2 - 38946473
SN - 0959-3985
VL - 41
SP - 752
EP - 762
JO - Physiotherapy Theory and Practice
JF - Physiotherapy Theory and Practice
IS - 4
ER -