Alkoholforbrug og risiko for leversygdom betydningen af køn Et Populationsstudie

Povl Ulrik Becker*, Allan Deis, Thorkild I.A. Sørensen, Morten N. Grønbaek, Knut Borch-Johnsen, Cecilia Florvall Müller, Peter Schnohr, Gorm Bøje Jensen

*Corresponding author af dette arbejde

    Publikation: Bidrag til tidsskriftArtikelForskningpeer review

    Abstract

    The association between self-reported alcohol intake and the risk of future liver disease was studied in a population-based prospective cohort of 13,285 men and women aged 30-79 years. Diagnoses indicating alcoholic liver disease (n=261) or cirrhosis (n=124) were obtained from the Danish National Health Registers. The cumulated observation time was 130,558 person-years. A dosedependent increase in risk of developing liver disease was observed with increasing alcohol intake, with the steepest increase among women. At an alcohol intake of 7-13 beverages per week for women and 14-27 beverages per week for men the relative risk was significantly greater than 1. Women had a significantly higher relative risk of developing alcohol related liver disease than men for any given level of alcohol intake. In the general population, self-reported current alcohol intake is a good predictor of the future risk of alcoholic liver disease.

    Bidragets oversatte titelPrédiction of risk of liver disease by alcohol intake, sex, and age: A prospective population study
    OriginalsprogDansk
    Sider (fra-til)3782-3786
    Antal sider5
    TidsskriftUgeskrift for laeger
    Vol/bind159
    Udgave nummer24
    StatusUdgivet - 1 dec. 1997

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