A remarkable hematological and molecular response pattern in a patient with polycythemia vera during combination therapy with simvastatin and alendronate

Anders Lindholm Sørensen, Klaus Kallenbach, Hans Carl Hasselbalch

Publikation: Bidrag til tidsskriftArtikelForskningpeer review

Abstrakt

We report a 57-year old man with polycythemia vera, who had a remarkable hematological and molecular response during treatment with simvastatin and alendronate. The patient was treated with this combination for 56 months, and during this period the patient has been in complete hematological remission. The JAK2-V617F allele burden has dropped from 64% to sustained values below 20%, and follow-up bone marrow biopsies have revealed no change in PV features, without any regular cytoreductive treatment.

OriginalsprogEngelsk
Sider (fra-til)20-23
Antal sider4
TidsskriftLeukemia Research Reports
Vol/bind6
DOI
StatusUdgivet - 1 jan. 2016

Fingeraftryk Udforsk hvilke forskningsemner 'A remarkable hematological and molecular response pattern in a patient with polycythemia vera during combination therapy with simvastatin and alendronate' indeholder.

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