A possible association between the genetic predisposition for dizygotic twinning and schizophrenia

Ulla Kläning; Carsten Bøcker Pedersen; Preben Bo Mortensen; Kirsten Ohm Kyvik; Axel Skytthe

doi:10.1016/S0920-9964(01)00343-7

A possible association between the genetic predisposition for dizygotic twinning and schizophrenia

Ulla Kläning
, Carsten Bøcker Pedersen
, Preben Bo Mortensen
, Kirsten Ohm Kyvik
, Axel Skytthe

Publikation: Bidrag til tidsskrift › Artikel › Forskning › peer review

Abstract

BACKGROUND: A previous study demonstrated a 40 Through record linkage between The Danish Twin Register, The Danish Psychiatric Central Register, and The Danish Civil Registration System, the rate of schizophrenia in singleton siblings of dizygotic and monozygotic twins was compared with the rate in siblings of singletons. RESULTS: The rate of first admission to hospital for schizophrenia in siblings of dizygotic twins was 35p = 0.04). The rate in siblings of monozygotic twins was not increased. CONCLUSION: The results are in accordance with a theory of a linkage between genes influencing the rate of dizygotic twinning and genes influencing the threshold for developing schizophrenia.

Originalsprog	Engelsk
Sider (fra-til)	31-35
Antal sider	5
Tidsskrift	Schizophrenia Research
Vol/bind	58
Udgave nummer	1
DOI	https://doi.org/10.1016/S0920-9964(01)00343-7
Status	Udgivet - 2002

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10.1016/S0920-9964(01)00343-7

Citationsformater

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title = "A possible association between the genetic predisposition for dizygotic twinning and schizophrenia",

abstract = "BACKGROUND: A previous study demonstrated a 40 Through record linkage between The Danish Twin Register, The Danish Psychiatric Central Register, and The Danish Civil Registration System, the rate of schizophrenia in singleton siblings of dizygotic and monozygotic twins was compared with the rate in siblings of singletons. RESULTS: The rate of first admission to hospital for schizophrenia in siblings of dizygotic twins was 35p = 0.04). The rate in siblings of monozygotic twins was not increased. CONCLUSION: The results are in accordance with a theory of a linkage between genes influencing the rate of dizygotic twinning and genes influencing the threshold for developing schizophrenia.",

keywords = "Cross-Sectional Studies, Denmark, Diseases in Twins, Female, Genetic Predisposition to Disease, Humans, Male, Registries, Risk Factors, Schizophrenia, Twins, Dizygotic, Monozygotic",

author = "Ulla Kl{\"a}ning and Pedersen, \{Carsten B{\o}cker\} and Mortensen, \{Preben Bo\} and Kyvik, \{Kirsten Ohm\} and Axel Skytthe",

year = "2002",

doi = "10.1016/S0920-9964(01)00343-7",

language = "English",

volume = "58",

pages = "31--35",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - A possible association between the genetic predisposition for dizygotic twinning and schizophrenia

AU - Kläning, Ulla

AU - Pedersen, Carsten Bøcker

AU - Mortensen, Preben Bo

AU - Kyvik, Kirsten Ohm

AU - Skytthe, Axel

PY - 2002

Y1 - 2002

N2 - BACKGROUND: A previous study demonstrated a 40 Through record linkage between The Danish Twin Register, The Danish Psychiatric Central Register, and The Danish Civil Registration System, the rate of schizophrenia in singleton siblings of dizygotic and monozygotic twins was compared with the rate in siblings of singletons. RESULTS: The rate of first admission to hospital for schizophrenia in siblings of dizygotic twins was 35p = 0.04). The rate in siblings of monozygotic twins was not increased. CONCLUSION: The results are in accordance with a theory of a linkage between genes influencing the rate of dizygotic twinning and genes influencing the threshold for developing schizophrenia.

AB - BACKGROUND: A previous study demonstrated a 40 Through record linkage between The Danish Twin Register, The Danish Psychiatric Central Register, and The Danish Civil Registration System, the rate of schizophrenia in singleton siblings of dizygotic and monozygotic twins was compared with the rate in siblings of singletons. RESULTS: The rate of first admission to hospital for schizophrenia in siblings of dizygotic twins was 35p = 0.04). The rate in siblings of monozygotic twins was not increased. CONCLUSION: The results are in accordance with a theory of a linkage between genes influencing the rate of dizygotic twinning and genes influencing the threshold for developing schizophrenia.

KW - Cross-Sectional Studies

KW - Denmark

KW - Diseases in Twins

KW - Female

KW - Genetic Predisposition to Disease

KW - Humans

KW - Male

KW - Registries

KW - Risk Factors

KW - Schizophrenia

KW - Twins

KW - Dizygotic

KW - Monozygotic

U2 - 10.1016/S0920-9964(01)00343-7

DO - 10.1016/S0920-9964(01)00343-7

M3 - Article

SN - 0920-9964

VL - 58

SP - 31

EP - 35

JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 1

ER -

A possible association between the genetic predisposition for dizygotic twinning and schizophrenia

Abstract

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