A comparison of pediatric and adult neuromyelitis optica spectrum disorders: A review of clinical manifestation, diagnosis, and treatment

Seyed Mohammad Baghbanian*, Nasrin Asgari, Mohammad Ali Sahraian, Abdorreza Naser Moghadasi

*Corresponding author af dette arbejde

Publikation: Bidrag til tidsskriftReviewForskningpeer review

Abstrakt

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disorder of the central nervous system (CNS). Serum immunoglobulin G autoantibodies (NMO-IgG) are identified in the majority of NMOSD patients. The Pediatric form presents before 18 years. Based on the similarity of clinical, neuroimaging, and laboratory characteristics of pediatric NMOSD to those of the adult form, the international panel suggested that adult criteria of NMOSD also are appropriate in pediatric patients. However, the proposed criteria need validation in pediatric patients. This strategy poses challenges to the study design in clinical trials in pediatric NMOSD patients.

OriginalsprogEngelsk
Sider (fra-til)222-231
Antal sider10
TidsskriftJournal of the Neurological Sciences
Vol/bind388
DOI
StatusUdgivet - 15 maj 2018

Fingeraftryk

Udforsk hvilke forskningsemner 'A comparison of pediatric and adult neuromyelitis optica spectrum disorders: A review of clinical manifestation, diagnosis, and treatment' indeholder.

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