Ætiologi og behandling af kronisk hjertesvigt med nedsat venstre ventrikelfunktion

Anders Hostrup Larsen; Trine Kiilerich Lauridsen; Julie Kiranjot K Vishram-Nielsen; Henrik Vase; Søren Vraa; Emil Wolsk; Anders Barasa; Helle Søholm; Lars Køber; Nadia Pia Paarup Dridi

doi:10.61409/V05240339

Ætiologi og behandling af kronisk hjertesvigt med nedsat venstre ventrikelfunktion

Anders Hostrup Larsen, Trine Kiilerich Lauridsen, Julie Kiranjot K Vishram-Nielsen, Henrik Vase, Søren Vraa, Emil Wolsk, Anders Barasa, Helle Søholm, Lars Køber, Nadia Pia Paarup Dridi^*

^*Corresponding author af dette arbejde

Kardiologisk Afdeling

Publikation: Bidrag til tidsskrift › Review › Forskning › peer review

Abstract

Heart failure with reduced ejection fraction is a syndrome consisting of symptoms (dyspnoea, fatigue, swelling) and/or signs of congestion (pulmonary crackles, oedema). It is caused by structural and/or functional pathologies, most commonly ischaemic heart disease, entailing elevated cardiac filling pressures and can result in low cardiac output. Medical treatment has evolved during the recent decades as outlined in this review, and a 4-pillar treatment strategy is recommended including a renin-angiotensin-aldosterone system blocker or sacubitril/valsartan, a betablocker, a mineralocorticoid antagonist, and an SGLT2 inhibitor.

Bidragets oversatte titel	Aetiology and treatment of chronic heart failure with reduced left ventricular function
Originalsprog	Dansk
Artikelnummer	V05240339
Antal sider	8
Tidsskrift	Ugeskrift for Laeger
Vol/bind	186
Udgave nummer	42
DOI	https://doi.org/10.61409/V05240339
Status	Udgivet - 14 okt. 2024

Emneord

Adrenergic beta-Antagonists/therapeutic use
Angiotensin Receptor Antagonists/therapeutic use
Angiotensin-Converting Enzyme Inhibitors/therapeutic use
Chronic Disease
Heart Failure/drug therapy
Humans
Mineralocorticoid Receptor Antagonists/therapeutic use
Sodium-Glucose Transporter 2 Inhibitors/therapeutic use
Stroke Volume
Ventricular Dysfunction, Left/drug therapy

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10.61409/V05240339Licens: CC BY-NC-ND

Citationsformater

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title = "{\AE}tiologi og behandling af kronisk hjertesvigt med nedsat venstre ventrikelfunktion",

abstract = "Heart failure with reduced ejection fraction is a syndrome consisting of symptoms (dyspnoea, fatigue, swelling) and/or signs of congestion (pulmonary crackles, oedema). It is caused by structural and/or functional pathologies, most commonly ischaemic heart disease, entailing elevated cardiac filling pressures and can result in low cardiac output. Medical treatment has evolved during the recent decades as outlined in this review, and a 4-pillar treatment strategy is recommended including a renin-angiotensin-aldosterone system blocker or sacubitril/valsartan, a betablocker, a mineralocorticoid antagonist, and an SGLT2 inhibitor.",

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author = "{Hostrup Larsen}, Anders and Lauridsen, {Trine Kiilerich} and Vishram-Nielsen, {Julie Kiranjot K} and Henrik Vase and S{\o}ren Vraa and Emil Wolsk and Anders Barasa and Helle S{\o}holm and Lars K{\o}ber and Dridi, {Nadia Pia Paarup}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2024",

month = oct,

day = "14",

doi = "10.61409/V05240339",

language = "Dansk",

volume = "186",

journal = "Ugeskrift for Laeger",

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publisher = "Almindelige Danske Laegeforening",

number = "42",

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TY - JOUR

T1 - Ætiologi og behandling af kronisk hjertesvigt med nedsat venstre ventrikelfunktion

AU - Hostrup Larsen, Anders

AU - Lauridsen, Trine Kiilerich

AU - Vishram-Nielsen, Julie Kiranjot K

AU - Vase, Henrik

AU - Vraa, Søren

AU - Wolsk, Emil

AU - Barasa, Anders

AU - Søholm, Helle

AU - Køber, Lars

AU - Dridi, Nadia Pia Paarup

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024/10/14

Y1 - 2024/10/14

N2 - Heart failure with reduced ejection fraction is a syndrome consisting of symptoms (dyspnoea, fatigue, swelling) and/or signs of congestion (pulmonary crackles, oedema). It is caused by structural and/or functional pathologies, most commonly ischaemic heart disease, entailing elevated cardiac filling pressures and can result in low cardiac output. Medical treatment has evolved during the recent decades as outlined in this review, and a 4-pillar treatment strategy is recommended including a renin-angiotensin-aldosterone system blocker or sacubitril/valsartan, a betablocker, a mineralocorticoid antagonist, and an SGLT2 inhibitor.

AB - Heart failure with reduced ejection fraction is a syndrome consisting of symptoms (dyspnoea, fatigue, swelling) and/or signs of congestion (pulmonary crackles, oedema). It is caused by structural and/or functional pathologies, most commonly ischaemic heart disease, entailing elevated cardiac filling pressures and can result in low cardiac output. Medical treatment has evolved during the recent decades as outlined in this review, and a 4-pillar treatment strategy is recommended including a renin-angiotensin-aldosterone system blocker or sacubitril/valsartan, a betablocker, a mineralocorticoid antagonist, and an SGLT2 inhibitor.

KW - Adrenergic beta-Antagonists/therapeutic use

KW - Angiotensin Receptor Antagonists/therapeutic use

KW - Angiotensin-Converting Enzyme Inhibitors/therapeutic use

KW - Chronic Disease

KW - Heart Failure/drug therapy

KW - Humans

KW - Mineralocorticoid Receptor Antagonists/therapeutic use

KW - Sodium-Glucose Transporter 2 Inhibitors/therapeutic use

KW - Stroke Volume

KW - Ventricular Dysfunction, Left/drug therapy

U2 - 10.61409/V05240339

DO - 10.61409/V05240339

M3 - Review

C2 - 39531028

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 42

M1 - V05240339

ER -

Ætiologi og behandling af kronisk hjertesvigt med nedsat venstre ventrikelfunktion

Abstract

Emneord

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